Optimization of peptide-based inhibitors targeting the HtrA serine protease in Chlamydia: Design, synthesis and biological evaluation of pyridone-based and N-Capping group-modified analogues

Research paper with supplementary materials documenting all data and results on series of chemical improvements to a molecule and in vitro testing. The data is stored on the University of Technology Sydney's e-research drive that is backed up to two separate servers and can be obtained by request to the data custodian.

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Title Optimization of peptide-based inhibitors targeting the HtrA serine protease in Chlamydia: Design, synthesis and biological evaluation of pyridone-based and N-Capping group-modified analogues
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Licence cc-by
Data Status
Update Frequency notPlanned
Landing Page https://data.nsw.gov.au/data/dataset/eb8b97f0-2e69-4905-b4f4-5034730a9dbc
Date Published 2025-02-18
Date Updated 2025-06-06
Contact Point
Temporal Coverage -
Geospatial Coverage {"type":"Polygon","coordinates":[[[140.8,-37.8],[140.8,-27.9],[153.7,-27.9],[153.7,-37.8],[140.8,-37.8]]]}
Jurisdiction
Data Portal Data.NSW
Publisher/Agency University of Technology Sydney (UTS)